Can a hybrid web app be built?

A hybrid web app meaning a coldbox mvc app + none mvc app.

Would like to buld an app that loads the user details based on their
username, e.g. domain.com/username while at the same time being able
to access different none mvc apps like: domain.com/app1 domain.com/
app2

How will the system know when a user profile is being requested, or
when an application is being requested based on the url?

If needed, you may ask for clarification.

Thank you for your contributions!