I've got a good one for you.
I'm using cfform format="flash" (don't ask why, it's required for this
When using either http://myurl.com/index.cfm/handler/method or
http://myurl.com/handler/method (I have url rewriting enabled in
apache - but even if I disable it, it doesn't make any difference),
the generated mxml.cfswf file shows up in firebug as 401 unknown.
As I said, if I use a different URL with the full event argument,
everything works fine.
It's not actually a really big deal - but I'd be interested to know
why it does that.