Is the request running for 5 minutes before throwing that error? If so, you will probably need to increase the to longer. Hopefully your app doesn’t actually take longer than 5 minutes to reinit though.
THE TIME HAS COME for you to improve you grasp of ColdFusion’s Request Timeouts! Only with this knowledge can you conquer your enemy and crush the bits with your war hammer! To aid you in your adventures, I have summoned the Gods of Search who are able to access vital resources that have been scattered across the interwebs by a great host of developers. You’re only companion in this adventure is your inquisitive mind–may it be sharp and ripe for harvest.
I present these gifts and bid you farewell on your adventure!